Myeloradiculitis with lupus-like autoimmunity following Sinovac COVID-19 vaccination

Authors

  • Yew Long Lo Department of Neurology, National Neuroscience Institute, Singapore General Hospital Campus
  • J J H Lam Department of Neurology, National Neuroscience Institute, Singapore General Hospital Campus
  • L L Chan Department of Neurology, National Neuroscience Institute, Singapore General Hospital Campus

DOI:

https://doi.org/10.54029/2021eyv

Keywords:

COVID-19, vaccination, complication, myeloradiculitis, lupus

Abstract

We report a 67 year old man with features in keeping with transverse myelitis, lumbar root and cauda equina involvement suggestive of delayed autoimmune pathogenesis after the Sinovac COVID-19 vaccination previously observed  in vaccines  containing viral antigens. Grossly elevated antinuclear antibody and anti-double-stranded DNA are in line with observations in lupus myelitis despite the lack of systemic manifestations.

Published

2022-01-01

Issue

Vol. 26 No. 4 (2021)

Section

Correspondence