Mild encephalopathy with reversible splenial lesion associated with SARS-CoV-2 infection: A case report

Fettah Eren; Gokhan  Ozdemir; Omer Faruk  Ildiz; Dilek  Ergun; Serefnur Ozturk

doi:10.54029/2021urw

Authors

Fettah Eren Department of Neurology, Selcuk University, School of Medicine, Konya, Turkey https://orcid.org/0000-0001-6834-0827
Gokhan Ozdemir Department of Neurology, Selcuk University, School of Medicine, Konya, Turkey https://orcid.org/0000-0001-8140-6333
Omer Faruk Ildiz Department of Neurology, Selcuk University, School of Medicine, Konya, Turkey https://orcid.org/0000-0002-4815-0919
Dilek Ergun Department of Chest Diseases, Selcuk University, School of Medicine, Konya, Turkey https://orcid.org/0000-0002-9890-2250
Serefnur Ozturk Department of Neurology, Selcuk University, School of Medicine, Konya, Turkey https://orcid.org/0000-0001-8986-155X

DOI:

https://doi.org/10.54029/2021urw

Keywords:

coronavirus, corpus callosum, SARS-COV-2, encephalopathy

Abstract

Mild encephalopathy with reversible splenial lesion (MERS) is characterized with a reversible lesion in the splenium of the corpus callosum. It has been defined as a neuro-radiologic syndrome associated with viral infections. In addition, this lesion may related with epileptic seizures, antiepileptic drugs or metabolic disturbances. We presented a patient with MERS associated with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Encephalopathy and psychiatric symptoms were the major initial clinical symptoms. Brain magnetic resonance imaging showed complete resolution of the corpus callosum lesion. The symptoms of patient recovered completely. Complete resolution of corpus callosum lesion and recovery of encephalopathy associated with SARS-COV-2 were similar to previous cases.

Mild encephalopathy with reversible splenial lesion associated with SARS-CoV-2 infection: A case report

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