Miller Fisher syndrome: A comprehensive review and clinical insights [2026] - 518KB
by Ji Wang, Kang Liu, Donghui Shen
Miller Fisher syndrome (MFS) is a variant of Guillain-Barré syndrome (GBS), characterized by the clinical triad of ophthalmoplegia, ataxia and areflexia. Anti-ganglioside GQ1b antibodies, detected in...

A narrative review of aging-targeted mechanisms and interventions in Alzheimer’s disease [2026] - 657KB
by Khaled A Abdel-Sater
Background & Objective: The biggest risk factor for Alzheimer’s disease (AD) is aging, contributing to impaired clearance of tau and amyloid-beta (Aβ) proteins, microglial senescence, endoplasmic r...

Clinical predictors of an acute stroke Vs. stroke mimic among code stroke patients: A single center retrospective study [2026] - 371KB
by Jose Leandro Tuason, Cymbeline Perez-Santiago
Background & Objective: There is an increasing rate of stroke mimics being identified in code stroke pathways, which adds to hospital staff workload and increased financial costs for patients. This st...

The value of serum ZAG levels in predicting the progression and prognosis of acute ischemic stroke [2026] - 706KB
by Xiaobo Li, Jingwen Wang, Ling Sun, Linlin Xie, Aipeng Hu, Xiaoyun Huang, Luhang Tao, Jing Hang, Xin Chen, Yuping Li, Hailong Yu
Objective: The aim of this study was to investigate the value of serum zinc-alpha2-glycoprotein (ZAG) levels in predicting the progression and prognosis of acute ischemic stroke (AIS). Methods: A tota...

Prognostic value of systemic immune-inflammation index (SII), systemic inflammation response index (SIRI) and white blood cell–mean platelet volume ratio (WMR) in predicting mortality in acute ischemic stroke [2026] - 404KB
by Buket Yılmaz, Abdurrahman Sönmezler
Background & Objective: Systemic inflammatory markers have recently gained attention as potential predictors of clinical outcomes in acute ischemic stroke. This study aimed to evaluate the prognostic ...

Acute anterior choroidal artery infarction: Clinical predictors of prognosis [2026] - 553KB
by Emre Kumral, Hüseyin Nezih Özdemir, Zeynep Yamazhan
Objectives: The clinical and prognostic features of acute anterior choroidal artery (AChA) stroke have not been sufficiently investigated in the context of new treatment approaches. Methods: This AChA...

Role of in-hospital blood pressure and stroke severity in predicting 3-month functional outcomes after acute ischemic stroke: Experience from a Malaysian tertiary centre [2026] - 400KB
by Mariyam Zaurath Abdulla, Rathika Rajah, Wan Nur Nafisah binti Wan Yahya, Wan Asyraf Bin Wan Zaidi, Zhe Kang Law, Juen Kiem Tan
Background & Objective: The optimal inpatient blood pressure (BP) target after acute ischemic stroke (AIS) remains uncertain, particularly in Asian populations. We evaluated whether mean in-hospital B...

Expression and significance of HMOX1, STAT3, ferritin, GPX4, and hs-CRP in patients with ischemic stroke [2026] - 420KB
by Li Chen, Lei Cui, Yi-Fei Ji, Xin Li
Background & Objective: Ischemic stroke (IS) is a leading cause of global mortality and disability, and as such, reliable biomarkers for its early diagnosis and prognosis are needed. This study explor...

Development and validation of a predictive model for pneumonia risk in ICU patients with stroke: A retrospective cohort study using the MIMIC-IV 3.0 database [2026] - 904KB
by Chenyang Shi, Jian Ye, Huiqing Zhou, Wei Lu, Jian Lan, Qingqing Chen, Cheng Zheng
Background: Stroke is a leading cause of death and disability worldwide, with poststroke complications such as pneumonia significantly increasing mortality and healthcare burden. Existing models for p...

Golden hours at risk: Prehospital delays in acute ischemic stroke and their impact on public awareness and emergency response [2026] - 397KB
by Burak Ozkan, Engin Ozakin, Atilla Ozcan Ozdemir, Nurdan Acar, M Evvah Karakılıc, Filiz Baloglu Kaya, Ezgi Baran, Nurettin Tekin, Ozlem Aykac, Volkan Ercan, Caglar Kuas, Mustafa Emin Canakci
Background: Timely intervention is essential in the management of acute ischemic stroke, as delays in treatment initiation can significantly worsen clinical outcomes. Despite advancements in stroke ca...